Some methodological issues in the implementation of subjective poverty definitions

Economics

Internationalisation and the valuation of forest assets

The paper looks at the implications of internationalisation of forest ownership on forest valuation. With an increase in the international diversity of forest owners questions are raised about the effect that this has on the methods used to value forests and whether there are substantive differences due to the nationality of the owner. A survey of 30 commercial forest owners in New Zealand and 27 commercial forest owners in Australia was carried out. The survey looked at factors such as the legal structure of the owner, whether it was involved in only forest ownership or forest ownership and wood processing, countries in which forest are owned, main species, predominant age class distribution and target rotation age of forests, and valuation method currently used. The results show that there are substantial differences in how forests are valued in either country, but also that these differences to not appear to be linked to the nationality of the owner

Toward in vitro fertilization in Brachiaria spp.

Brachiaria are forage grasses widely cultivated in tropical areas. In vitro pollination was applied to accessions of Brachiaria spp. by placing pollen of non-dehiscent anthers on a solid medium near isolated ovaries. Viability and in vitro germination were tested in order to establish good conditions for pollen development. Comparing sexual to apomictic plants, apomictic pollen has more abortion after meiosis during the microspore stage and a lower viability and, of both types, only some plants have sufficient germination in a high sugar concentration. Using in vitro pollination with the sexual plant, the pollen tube penetrates into the nucellus and micropyle, but the embryo sac degenerates and collapses. In the apomictic B. decumbens, in vitro pollination leads to the transfer of the sperm nuclei into the egg cell and the central cell. The results are discussed according to normal fertilization and barriers in sexual and apomictic plants

Minor industrial crops in the Southern Africa region: an appraisal of developmental potential with special reference to interregional trade. (June-July 1995). Vol.1: The main report

This report presents the findings and conclusions arising from a team study carried out in June-August 1995 of the potential for development of 'minor industrial crops' in the Southern Africa region. The study focussed on spices, essential oils, gums, resins, natural colourants and castor oil. Information was gathered on markets and production by means of field studies in South Africa, Malawi, Zimbabwe and Zambia and was supplemented by examination of trade statistics and discussions with overseas traders. Time constraints on the study precluded a thorough investigation of all topics and, therefore, the conclusions reached must be regarded as a first phase overview of the regional market and a preliminary identification of the more promising crops for future development

Krimpbeleid met sociale media : sturen met sociaal kapitaal op maatschappelijke energie

Naarmate het besef groeit dat de zorgsamenleving onbetaalbaar wordt onder invloed van de demografische en economische trends, komt sociale en maatschappelijke innovatie steeds nadrukkelijker op de agenda. In alle sectoren van het rijksbeleid wordt gesproken van vermaatschappelijking als belangrijke strategie en doorsnijdend thema. Het besef dat marktwerking en new public management (de overheidsdienst als bedrijf) de consumptieve houding van burgers hebben versterkt, ligt ten grondslag aan deze strategie. Het maatschappelijk initiatief is er nog steeds en kan als een soort humuslaag de voedingsbodem vormen van een actieve samenleving waarin de overheid verantwoordelijk is voor de infrastructuur, en burgers c.q. het maatschappelijk middenveld voor specifieke doelen. In het Noord-Groningse dorpje Holwierde kan de dorpswinkel open blijven, omdat verstandelijk gehandicapten bij wijze van dagbesteding meehelpen: een mooi voorbeeld van zo’n sociale innovatie in die humuslaag. In dit essay gaan we na hoe die humuslaag is ingebed in sociale-media-communicatiepraktijken en welke nieuwe mogelijkheden dit kan bieden voor het beleid inzake krimp. Hiervoor hebben we onderzoek gedaan, waarbij in de pilotgebieden Burgerschap in Krimp van BZK en de Landelijke Vereniging van Kleine Kernen (LVKK) is gekeken naar discussies over krimp en zelforganisatie

The diverse nature of island isolation and its effect on land bridge insular faunas

Aim: Isolation is a key factor in island biology. It is usually defined as the distance to the geographically nearest mainland, but many other definitions exist. We explored how testing different isolation indices affects the inference of impacts of isolation on faunal characteristics. We focused on land bridge islands and compared the relationships of many spatial and temporal (i.e., through time) isolation indices with community‐, population‐ and individual‐level characteristics (species richness, population density and body size, respectively). Location: Aegean Sea islands, Greece. Time period: Current. Taxon: Many animal taxa. Methods: We estimated 21 isolation indices for 205 islands and recorded species richness data for 15 taxa (invertebrates and vertebrates). We obtained body size data for seven lizard species and population density data for three. We explored how well indices predict each characteristic, in each taxon, by conducting a series of ordinary least squares regressions (controlling for island area when needed) and a meta‐analysis. Results: Isolation was significantly (and negatively) associated with species richness in 10 of 15 taxa. It was significantly (and positively) associated with body size in only one of seven species and was not associated with population density. The effect of isolation on species richness was much weaker than that of island area, regardless of the index tested. Spatial indices generally out‐performed temporal indices, and indices directly related to the mainland out‐performed those related mainly to neighbouring islands. No index was universally superior to others, including the distance to the geographically nearest mainland. Main conclusions: The choice of index can alter our perception of the impacts of isolation on biological patterns. The nearly automatic, ubiquitous use of distance to the geographically nearest mainland misrepresents the complexity of the effects of isolation. We recommend the simultaneous testing of several indices that represent different aspects of isolation, in order to produce more constructive and thorough investigations and avoid imprecise inference

Advances in guava propagation.

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Bosutinib in Resistant and Intolerant Pediatric Patients With Chronic Phase Chronic Myeloid Leukemia: Results From the Phase I Part of Study ITCC054/COG AAML1921

Pediatric patients; Intolerant; Chronic myeloid leukemiaPacientes pediátricos; Intolerantes; Leucemia mieloide crónicaPacients pediàtrics; Intolerants; Leucèmia mieloide crònicaPurpose Bosutinib is approved for adults with chronic myeloid leukemia (CML): 400 mg once daily in newly diagnosed (ND); 500 mg once daily in resistant/intolerant (R/I) patients. Bosutinib has a different tolerability profile than other tyrosine kinase inhibitors (TKIs) and potentially less impact on growth (preclinical data). The primary objective of this first-in-child trial was to determine the recommended phase II dose (RP2D) for pediatric R/I and ND patients. Patients and Methods In the phase I part of this international, open-label trial (ClinicalTrials.gov identifier: NCT04258943), children age 1-18 years with R/I (per European LeukemiaNet 2013) Ph+ CML were enrolled using a 6 + 4 design, testing 300, 350, and 400 mg/m2 once daily with food. The RP2D was the dose resulting in 0/6 or 1/10 dose-limiting toxicities (DLTs) during the first cycle and achieving adult target AUC levels for the respective indication. As ND participants were only enrolled in phase II, the ND RP2D was selected based on data from R/I patients. Results Thirty patients were enrolled; 27 were evaluable for DLT: six at 300 mg/m2, 11 at 350 mg/m2 (one DLT), and 10 at 400 mg/m2 (one DLT). The mean AUCs at 300 mg/m2, 350 mg/m2, and 400 mg/m2 were 2.20 μg h/mL, 2.52 μg h/mL, and 2.66 μg h/mL, respectively. The most common adverse event was diarrhea (93%; ≥grade 3: 11%). Seven patients stopped because of intolerance and eight because of insufficient response. Complete cytogenetic and major molecular response to bosutinib appeared comparable with other published phase I/II trials with second-generation TKIs in children. Conclusion Bosutinib was safe and effective. The pediatric RP2D was 400 mg/m2 once daily (max 600 mg/d) with food in R/I patients and 300 mg/m2 once daily (max 500 mg/d) with food in ND patients, which achieved targeted exposures as per adult experience.Sponsorship for the study was provided by Erasmus MC/Sophia Children's Hospital, Department of Pediatrics, Rotterdam, the Netherlands